LMPD Database

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LMP004799

UniProt Annotations

Entry Information
Gene NameN(alpha)-acetyltransferase 20, NatB catalytic subunit
Protein EntryNAA20_MOUSE
UniProt IDP61600
SpeciesMouse
Comments
Comment typeDescription
Catalytic ActivityAcetyl-CoA + peptide = N(alpha)-acetylpeptide + CoA.
FunctionCatalytic subunit of the NatB complex which catalyzes acetylation of the N-terminal methionine residues of peptides beginning with Met-Asp, Met-Glu, Met-Asn and Met-Gln. Proteins with cell cycle functions are overrepresented in the pool of NatB substrates. Required for maintaining the structure and function of actomyosin fibers and for proper cellular migration (By similarity). {ECO:0000250}.
SimilarityBelongs to the acetyltransferase family. ARD1 subfamily. {ECO:0000305}.
SimilarityContains 1 N-acetyltransferase domain. {ECO:0000255|PROSITE-ProRule:PRU00532}.
Subcellular LocationCytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.
SubunitComponent of the N-terminal acetyltransferase B (NatB) complex which is composed of NAA20 and NAA25. {ECO:0000250}.