LMPD Database

LMP004768

UniProt Annotations

Entry Information
Gene Namephosphatidylinositol glycan anchor biosynthesis, class Z
Protein EntryPIGZ_MOUSE
UniProt IDQ8BTP0
SpeciesMouse
Comments
Comment typeDescription
FunctionMannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers a fourth mannose to some trimannosyl-GPIs during GPI precursor assembly. The presence of a fourth mannose in GPI is facultative and only scarcely detected, suggesting that it only exists in some tissues (By similarity). {ECO:0000250}.
PathwayGlycolipid biosynthesis; glycosylphosphatidylinositol- anchor biosynthesis.
SimilarityBelongs to the glycosyltransferase 22 family. PIGZ subfamily. {ECO:0000305}.
Subcellular LocationEndoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.