LMPD Database

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LMP004641

UniProt Annotations

Entry Information
Gene Namenicotinamide riboside kinase 1
Protein EntryNRK1_MOUSE
UniProt IDQ91W63
SpeciesMouse
Comments
Comment typeDescription
Catalytic ActivityATP + 1-(beta-D-ribofuranosyl)-nicotinamide = ADP + beta-nicotinamide D-ribonucleotide.
Catalytic ActivityATP + beta-D-ribosylnicotinate = ADP + nicotinate beta-D-ribonucleotide.
FunctionCatalyzes the phosphorylation of nicotinamide riboside (NR) and nicotinic acid riboside (NaR) to form nicotinamide mononucleotide (NMN) and nicotinic acid mononucleotide (NaMN). {ECO:0000250}.
PathwayCofactor biosynthesis; NAD(+) biosynthesis.
SimilarityBelongs to the uridine kinase family. NRK subfamily. {ECO:0000305}.
SubunitMonomer. {ECO:0000250}.