LMPD Database

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LMP004595

UniProt Annotations

Entry Information
Gene Namehedgehog acyltransferase
Protein EntryHHAT_HUMAN
UniProt IDQ5VTY9
SpeciesHuman
Comments
Comment typeDescription
Alternative ProductsEvent=Alternative splicing; Named isoforms=7; Name=1; IsoId=Q5VTY9-1; Sequence=Displayed; Name=2; IsoId=Q5VTY9-2; Sequence=VSP_016686, VSP_016689; Name=3; IsoId=Q5VTY9-3; Sequence=VSP_016689; Note=No experimental confirmation available.; Name=4; IsoId=Q5VTY9-4; Sequence=VSP_016685, VSP_016687, VSP_016688; Name=5; IsoId=Q5VTY9-5; Sequence=VSP_016686; Note=No experimental confirmation available.; Name=6; IsoId=Q5VTY9-6; Sequence=VSP_043481; Note=No experimental confirmation available.; Name=7; IsoId=Q5VTY9-7; Sequence=VSP_044968; Note=No experimental confirmation available.;
FunctionCatalyzes N-terminal palmitoylation of SHH; which is required for SHH signaling (By similarity). May bind GTP.
SimilarityBelongs to the membrane-bound acyltransferase family. HHAT subfamily.
Subcellular LocationEndoplasmic reticulum membrane {ECO
Tissue SpecificityUbiquitously expressed in normal tissues and cancer cell lines.