LMPD Database

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LMP004551

UniProt Annotations

Entry Information
Gene Nameneutral sphingomyelinase (N-SMase) activation associated factor
Protein EntryFAN_MOUSE
UniProt IDO35242
SpeciesMouse
Comments
Comment typeDescription
FunctionCouples the p55 TNF-receptor (TNF-R55 / TNFR1) to neutral sphingomyelinase (N-SMASE). Specifically binds to the N- smase activation domain of TNF-R55. May regulate ceramide production by N-SMASE.
SimilarityContains 1 BEACH domain. {ECO:0000255|PROSITE- ProRule:PRU00026}.
SimilarityContains 1 GRAM domain. {ECO:0000305}.
SimilarityContains 6 WD repeats. {ECO:0000255|PROSITE- ProRule:PRU00221}.