LMPD Database

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LMP004426

UniProt Annotations

Entry Information
Gene Namecannabinoid receptor 1 (brain)
Protein EntryCNR1_MOUSE
UniProt IDP47746
SpeciesMouse
Comments
Comment typeDescription
FunctionInvolved in cannabinoid-induced CNS effects. Acts by inhibiting adenylate cyclase. Could be a receptor for anandamide. Inhibits L-type Ca(2+) channel current.
PtmPalmitoylation at Cys-416 is important for recruitment at both plasma membrane and lipid rafts. {ECO:0000250}.
SimilarityBelongs to the G-protein coupled receptor 1 family. {ECO:0000255|PROSITE-ProRule:PRU00521}.
Subcellular LocationCell membrane; Multi-pass membrane protein.
SubunitInteracts (via C-terminus) with CNRIP1. {ECO:0000250}.