LMPD Database

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LMP004132

UniProt Annotations

Entry Information
Gene NameUDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 4
Protein EntryB4GT4_MOUSE
UniProt IDQ9JJ04
SpeciesMouse
Comments
Comment typeDescription
Catalytic ActivityUDP-alpha-D-galactose + N-acetyl-beta-D- glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl- (1<->1)-ceramide = UDP + beta-D-galactosyl-(1->4)-N-acetyl-beta-D- glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl- (1<->1)-ceramide.
Catalytic ActivityUDP-alpha-D-galactose + N-acetyl-D-glucosamine = UDP + N-acetyllactosamine.
CofactorName=Mn(2+); Xref=ChEBI:CHEBI:29035; Evidence={ECO:0000250};
FunctionResponsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids. {ECO:0000250}.
PathwayProtein modification; protein glycosylation.
Sequence CautionSequence=BAC32433.1; Type=Frameshift; Positions=321; Evidence={ECO:0000305};
SimilarityBelongs to the glycosyltransferase 7 family. {ECO:0000305}.
Subcellular LocationGolgi apparatus, Golgi stack membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}. Note=Trans cisternae of Golgi stack. {ECO:0000250}.
Web ResourceName=Functional Glycomics Gateway - GTase; Note=b4GalT4; URL="http://www.functionalglycomics.org/glycomics/molecule/jsp/glycoEnzyme/viewGlycoEnzyme.jsp?gbpId=gt_mou_463";