LMPD Database

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LMP003995

UniProt Annotations

Entry Information
Gene Nameheterogeneous nuclear ribonucleoprotein L-like
Protein EntryHNRLL_MOUSE
UniProt IDQ921F4
SpeciesMouse
Comments
Comment typeDescription
Alternative ProductsEvent=Alternative splicing; Named isoforms=3; Name=1; IsoId=Q921F4-1; Sequence=Displayed; Name=2; IsoId=Q921F4-4; Sequence=VSP_013290, VSP_013291; Note=No experimental confirmation available.; Name=3; IsoId=Q921F4-5; Sequence=VSP_026132, VSP_026133;
FunctionRNA-binding protein that functions as regulator of alternative splicing for multiple target mRNAs, including PTPRC/CD45 and STAT5A. Required for alternative splicing of PTPRC. {ECO:0000269|PubMed:19100700}.
InductionUp-regulated in stimulated T-cells. {ECO:0000269|PubMed:19100700}.
PtmIsoform 3 is phosphorylated at 'Ser-64'.
Sequence CautionSequence=BAE27500.1; Type=Erroneous initiation; Evidence={ECO:0000305};
SimilarityContains 3 RRM (RNA recognition motif) domains. {ECO:0000255|PROSITE-ProRule:PRU00176}.
SubunitInteracts with HNRNPL. {ECO:0000250}.