LMPD Database

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LMP003907

UniProt Annotations

Entry Information
Gene Nametransmembrane protein 55A
Protein EntryTM55A_HUMAN
UniProt IDQ8N4L2
SpeciesHuman
Comments
Comment typeDescription
Catalytic Activity1-phosphatidyl-1D-myo-inositol 4,5- bisphosphate + H(2)O = 1-phosphatidyl-1D-myo-inositol 5-phosphate + phosphate.
Catalytic Activity1-phosphatidyl-myo-inositol 4,5-bisphosphate + H(2)O = 1-phosphatidyl-1D-myo-inositol 5-phosphate + phosphate.
FunctionCatalyzes the hydrolysis of the 4-position phosphate of phosphatidylinositol 4,5-bisphosphate. Does not hydrolyze phosphatidylinositol 3,4,5-trisphosphate, phosphatidylinositol 3,4-bisphosphate, inositol 3,5-bisphosphate, inositol 3,4- bisphosphate, phosphatidylinositol 5-monophosphate, phosphatidylinositol 4-monophosphate and phosphatidylinositol 3- monophosphate.
Subcellular LocationLate endosome membrane ; Multi-pass membrane protein . Lysosome membrane ; Multi-pass membrane protein .
Tissue SpecificityUbiquitous.