LMPD Database

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LMP003885

UniProt Annotations

Entry Information
Gene Nameestablishment of cohesion 1 homolog 2 (S. cerevisiae)
Protein EntryESCO2_MOUSE
UniProt IDQ8CIB9
SpeciesMouse
Comments
Comment typeDescription
FunctionAcetyltransferase required for the establishment of sister chromatid cohesion. Couples the processes of cohesion and DNA replication to ensure that only sister chromatids become paired together. In contrast to the structural cohesins, the deposition and establishment factors are required only during the S phase. Acetylates the cohesin component SMC3 (By similarity). {ECO:0000250}.
Sequence CautionSequence=BAB26905.1; Type=Erroneous termination; Positions=481; Note=Translated as Glu.; Evidence={ECO:0000305};
SimilarityBelongs to the acetyltransferase family. ECO subfamily. {ECO:0000305}.
Subcellular LocationNucleus {ECO:0000250}. Chromosome {ECO:0000250}.