LMPD Database

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LMP003829

UniProt Annotations

Entry Information
Gene Namephosphatidylinositol glycan anchor biosynthesis, class H
Protein EntryPIGH_MOUSE
UniProt IDQ5M9N4
SpeciesMouse
Comments
Comment typeDescription
Catalytic ActivityUDP-N-acetyl-D-glucosamine + 1-phosphatidyl- 1D-myo-inositol = UDP + 6-(N-acetyl-alpha-D-glucosaminyl)-1- phosphatidyl-1D-myo-inositol.
FunctionPart of the complex catalyzing the transfer of N- acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis. {ECO:0000250}.
PathwayGlycolipid biosynthesis; glycosylphosphatidylinositol- anchor biosynthesis.
SimilarityBelongs to the PIGH family. {ECO:0000305}.
Subcellular LocationCytoplasm {ECO:0000250}.
SubunitAssociates with PIGA, PIGC, PIGP, PIGQ and DPM2. The latter is not essential for activity (By similarity). {ECO:0000250}.