LMPD Database

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LMP003778

UniProt Annotations

Entry Information
Gene Namepalmitoyl-protein thioesterase 1
Protein EntryPPT1_MOUSE
UniProt IDO88531
SpeciesMouse
Comments
Comment typeDescription
Catalytic ActivityPalmitoyl-[protein] + H(2)O = palmitate + [protein].
FunctionRemoves thioester-linked fatty acyl groups such as palmitate from modified cysteine residues in proteins or peptides during lysosomal degradation. Prefers acyl chain lengths of 14 to 18 carbons.
PtmGlycosylated.
Sequence CautionSequence=AAC25398.1; Type=Erroneous initiation; Evidence={ECO:0000305};
SimilarityBelongs to the palmitoyl-protein thioesterase family. {ECO:0000305}.
Subcellular LocationLysosome.
Tissue SpecificityHighest level in testis and kidney, lower in heart, brain and lung and lowest in skeletal muscle.