LMPD Database

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LMP003162

UniProt Annotations

Entry Information
Gene Namephosphatidic acid phosphatase type 2 domain containing 3
Protein EntryPPAC3_HUMAN
UniProt IDQ8NBV4
SpeciesHuman
Comments
Comment typeDescription
FunctionPlays a role as negative regulator of myoblast differentiation, in part through effects on MTOR signaling. Has no detectable enzymatic activity (By similarity).
Sequence CautionSequence=CAI16274.1; Type=Erroneous gene model prediction; Evidence= ;
SimilarityBelongs to the PA-phosphatase related phosphoesterase family.
Subcellular LocationNucleus envelope. Endoplasmic reticulum membrane. Membrane; Multi-pass membrane protein. Note=Both the N- and C-terminal are exposed to the cytoplasm/nucleoplasm.
SubunitHomo and heterooligomer. Interacts with MTOR; controls MTOR-dependent IGF2 expression during myoblast differentiation (By similarity).