LMPD Database

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LMP003119

UniProt Annotations

Entry Information
Gene Namelipolysis stimulated lipoprotein receptor
Protein EntryLSR_HUMAN
UniProt IDQ86X29
SpeciesHuman
Comments
Comment typeDescription
Alternative ProductsEvent=Alternative splicing; Named isoforms=6; Name=1; IsoId=Q86X29-1; Sequence=Displayed; Name=2; IsoId=Q86X29-2; Sequence=VSP_019691, VSP_019693; Name=3; IsoId=Q86X29-3; Sequence=VSP_019692, VSP_019694; Name=4; IsoId=Q86X29-4; Sequence=VSP_019692; Name=5; IsoId=Q86X29-5; Sequence=VSP_046797; Note=No experimental confirmation available.; Name=6; IsoId=Q86X29-6; Sequence=VSP_057210, VSP_057211; Note=No experimental confirmation available;
CautionIn contrast to the rodent orthologous protein, it is longer in N-terminus and no signal sequence is detected by any prediction method.
FunctionProbable role in the clearance of triglyceride-rich lipoprotein from blood. Binds chylomicrons, LDL and VLDL in presence of free fatty acids and allows their subsequent uptake in the cells (By similarity).
Sequence CautionSequence=AAB51178.1; Type=Erroneous gene model prediction; Evidence= ; Sequence=AAB58317.1; Type=Erroneous gene model prediction; Evidence= ; Sequence=AAH04381.2; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence= ;
SimilarityBelongs to the immunoglobulin superfamily. LISCH7 family.
SimilarityContains 1 Ig-like V-type (immunoglobulin-like) domain.
Subcellular LocationCell membrane ; Single-pass membrane protein .
SubunitHomotrimer or homotetramer.