LMPD Database

LMP002945

Gene Information

Entrez Gene ID5580
Gene Nameprotein kinase C, delta
Gene SymbolPRKCD
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005911 IEA:EnsemblCcell-cell junction
GO:0005737 IDA:UniProtKBCcytoplasm
GO:0005829 IDA:UniProtKBCcytosol
GO:0005783 IDA:UniProtKBCendoplasmic reticulum
GO:0070062 IDA:UniProtCextracellular vesicular exosome
GO:0005739 IEA:UniProtKB-KWCmitochondrion
GO:0016363 IEA:EnsemblCnuclear matrix
GO:0005654 TAS:ReactomeCnucleoplasm
GO:0005634 IDA:UniProtKBCnucleus
GO:0005886 IDA:UniProtKBCplasma membrane
GO:0005524 IEA:UniProtKB-KWFATP binding
GO:0004699 TAS:BHF-UCLFcalcium-independent protein kinase C activity
GO:0008047 IDA:UniProtKBFenzyme activator activity
GO:0019899 IPI:UniProtKBFenzyme binding
GO:0043560 ISS:BHF-UCLFinsulin receptor substrate binding
GO:0046872 IEA:UniProtKB-KWFmetal ion binding
GO:0004715 IEA:UniProtKB-ECFnon-membrane spanning protein tyrosine kinase activity
GO:0004697 ISS:UniProtKBFprotein kinase C activity
GO:0004674 IDA:UniProtKBFprotein serine/threonine kinase activity
GO:0007202 TAS:ReactomePactivation of phospholipase C activity
GO:0006915 IDA:UniProtKBPapoptotic process
GO:0042100 IEA:EnsemblPB cell proliferation
GO:0007596 TAS:ReactomePblood coagulation
GO:0007049 IEA:UniProtKB-KWPcell cycle
GO:0006921 TAS:ReactomePcellular component disassembly involved in execution phase of apoptosis
GO:0090398 IMP:BHF-UCLPcellular senescence
GO:0019221 TAS:ReactomePcytokine-mediated signaling pathway
GO:0042742 ISS:UniProtKBPdefense response to bacterium
GO:0007173 TAS:ReactomePepidermal growth factor receptor signaling pathway
GO:0038096 TAS:ReactomePFc-gamma receptor signaling pathway involved in phagocytosis
GO:0008543 TAS:ReactomePfibroblast growth factor receptor signaling pathway
GO:0010467 TAS:ReactomePgene expression
GO:0016064 IEA:EnsemblPimmunoglobulin mediated immune response
GO:0045087 TAS:ReactomePinnate immune response
GO:0060333 TAS:ReactomePinterferon-gamma-mediated signaling pathway
GO:0032613 IEA:EnsemblPinterleukin-10 production
GO:0032615 IEA:EnsemblPinterleukin-12 production
GO:0008631 TAS:ParkinsonsUK-UCLPintrinsic apoptotic signaling pathway in response to oxidative stress
GO:0016071 TAS:ReactomePmRNA metabolic process
GO:0030837 ISS:UniProtKBPnegative regulation of actin filament polymerization
GO:0051490 ISS:UniProtKBPnegative regulation of filopodium assembly
GO:0034351 IMP:UniProtKBPnegative regulation of glial cell apoptotic process
GO:0050728 IC:BHF-UCLPnegative regulation of inflammatory response
GO:0046627 ISS:BHF-UCLPnegative regulation of insulin receptor signaling pathway
GO:0043407 IMP:BHF-UCLPnegative regulation of MAP kinase activity
GO:0050732 ISS:BHF-UCLPnegative regulation of peptidyl-tyrosine phosphorylation
GO:0090331 ISS:UniProtKBPnegative regulation of platelet aggregation
GO:0032091 TAS:BHF-UCLPnegative regulation of protein binding
GO:0048011 TAS:ReactomePneurotrophin TRK receptor signaling pathway
GO:0042119 IDA:UniProtKBPneutrophil activation
GO:0018107 IDA:UniProtKBPpeptidyl-threonine phosphorylation
GO:0030168 TAS:ReactomePplatelet activation
GO:2001235 IEA:EnsemblPpositive regulation of apoptotic signaling pathway
GO:2000304 IMP:BHF-UCLPpositive regulation of ceramide biosynthetic process
GO:2000753 IMP:BHF-UCLPpositive regulation of glucosylceramide catabolic process
GO:1900163 IMP:UniProtKBPpositive regulation of phospholipid scramblase activity
GO:0035307 IMP:BHF-UCLPpositive regulation of protein dephosphorylation
GO:2001022 IMP:UniProtKBPpositive regulation of response to DNA damage stimulus
GO:2000755 IMP:BHF-UCLPpositive regulation of sphingomyelin catabolic process
GO:0032930 IMP:UniProtKBPpositive regulation of superoxide anion generation
GO:0006468 IDA:UniProtKBPprotein phosphorylation
GO:0050821 NAS:UniProtKBPprotein stabilization
GO:0010469 TAS:BHF-UCLPregulation of receptor activity
GO:0016070 TAS:ReactomePRNA metabolic process
GO:0007165 TAS:ReactomePsignal transduction
GO:0023021 IMP:BHF-UCLPtermination of signal transduction
KEGG Pathway Links
KEGG Pathway IDDescription
hsa04915Estrogen signaling pathway
hsa04750Inflammatory mediator regulation of TRP channels