LMPD Database

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LMP002936

UniProt Annotations

Entry Information
Gene Namezinc finger, DHHC domain containing 15
Protein EntryZDH15_MOUSE
UniProt IDQ8BGJ0
SpeciesMouse
Comments
Comment typeDescription
Catalytic ActivityPalmitoyl-CoA + [protein]-L-cysteine = [protein]-S-palmitoyl-L-cysteine + CoA.
DomainThe DHHC domain is required for palmitoyltransferase activity.
Enzyme RegulationInhibited by 2-bromopalmitate. {ECO:0000269|PubMed:15603741}.
FunctionPalmitoyltransferase specific for GAP43 and DLG4/PSD95. {ECO:0000269|PubMed:15603741}.
PtmAutopalmitoylated.
SimilarityBelongs to the DHHC palmitoyltransferase family. {ECO:0000305}.
SimilarityContains 1 DHHC-type zinc finger. {ECO:0000255|PROSITE-ProRule:PRU00067}.
Subcellular LocationMembrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Tissue SpecificityExpressed mainly in brain. {ECO:0000269|PubMed:15603741}.