LMPD Database

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LMP002935

UniProt Annotations

Entry Information
Gene Nameprogesterone receptor membrane component 1
Protein EntryPGRC1_HUMAN
UniProt IDO00264
SpeciesHuman
Comments
Comment typeDescription
Alternative ProductsEvent=Alternative splicing; Named isoforms=2; Name=1; IsoId=O00264-1; Sequence=Displayed; Name=2; IsoId=O00264-2; Sequence=VSP_054710; Note=No experimental confirmation available.;
DomainThe cytochrome b5 heme-binding domain lacks the conserved iron-binding His residues at positions 107 and 131.
FunctionReceptor for progesterone.
InteractionP00181:CYP2C2 (xeno); NbExp=6; IntAct=EBI-1045534, EBI-4320576; P16435:POR; NbExp=5; IntAct=EBI-1045534, EBI-726554;
SimilarityBelongs to the cytochrome b5 family. MAPR subfamily.
SimilarityContains 1 cytochrome b5 heme-binding domain.
Subcellular LocationMicrosome membrane ; Single- pass membrane protein . Endoplasmic reticulum membrane ; Single-pass membrane protein .
Tissue SpecificityWidely expressed, with highest expression in liver and kidney.