LMPD Database

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LMP002830

UniProt Annotations

Entry Information
Gene Name7-dehydrocholesterol reductase
Protein EntryDHCR7_MOUSE
UniProt IDO88455
SpeciesMouse
Comments
Comment typeDescription
Catalytic ActivityCholesterol + NADP(+) = cholesta-5,7-dien-3- beta-ol + NADPH.
FunctionProduction of cholesterol by reduction of C7-C8 double bond of 7-dehydrocholesterol (7-DHC).
PathwaySteroid biosynthesis; cholesterol biosynthesis.
SimilarityBelongs to the ERG4/ERG24 family. {ECO:0000305}.
Subcellular LocationEndoplasmic reticulum membrane; Multi-pass membrane protein.