LMPD Database

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LMP002813

UniProt Annotations

Entry Information
Gene NameST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5
Protein EntryQ3TRR3_MOUSE
UniProt IDQ3TRR3
SpeciesMouse
Comments
Comment typeDescription
Alternative ProductsEvent=Alternative splicing; Named isoforms=3; Name=V-L; Synonyms=Long; IsoId=P70126-1; Sequence=Displayed; Name=V-M; Synonyms=Middle; IsoId=P70126-2; Sequence=VSP_001789; Name=V-S; Synonyms=Short; IsoId=P70126-3; Sequence=VSP_001790;
FunctionMay be involved in the synthesis of gangliosides GD1c, GT1a, GQ1b and GT3 from GD1a, GT1b, GM1b and GD3 respectively.
PathwayProtein modification; protein glycosylation.
SimilarityBelongs to the glycosyltransferase 29 family. {ECO:0000305}.
Subcellular LocationGolgi apparatus membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}.
Tissue SpecificityHighly expressed in brain. Expressed at low levels in other tissues, including liver, testis, lung, placenta and spleen.
Web ResourceName=Functional Glycomics Gateway - GTase; Note=ST8Sia V; URL="http://www.functionalglycomics.org/glycomics/molecule/jsp/glycoEnzyme/viewGlycoEnzyme.jsp?gbpId=gt_mou_660";