LMPD Database

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LMP002801

UniProt Annotations

Entry Information
Gene Namecardiolipin synthase 1
Protein EntryCRLS1_HUMAN
UniProt IDQ9UJA2
SpeciesHuman
Comments
Comment typeDescription
Alternative ProductsEvent=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q9UJA2-1; Sequence=Displayed; Name=2; IsoId=Q9UJA2-2; Sequence=VSP_041398, VSP_041399; Note=No experimental confirmation available.;
Catalytic Activity2 Phosphatidylglycerol = diphosphatidylglycerol + glycerol.
FunctionCatalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
SimilarityBelongs to the CDP-alcohol phosphatidyltransferase class-I family.
Subcellular LocationMitochondrion inner membrane ; Multi-pass membrane protein .
Tissue SpecificityHighly expressed in tissues such as heart, skeletal muscle and liver.