LMPD Database

LMP002628

Gene Information

Entrez Gene ID	1901
Gene Name	sphingosine-1-phosphate receptor 1
Gene Symbol	S1PR1
Species	Homo sapiens

Gene Ontology (GO Annotations)

GO ID	Source	Type	Description
GO:0005768	IEA:UniProtKB-KW	C	endosome
GO:0009897	IEA:Ensembl	C	external side of plasma membrane
GO:0016021	IEA:UniProtKB-KW	C	integral component of membrane
GO:0031226	IDA:UniProtKB	C	intrinsic component of plasma membrane
GO:0005886	TAS:Reactome	C	plasma membrane
GO:0004930	TAS:ProtInc	F	G-protein coupled receptor activity
GO:0001664	IPI:UniProtKB	F	G-protein coupled receptor binding
GO:0046625	IEA:Ensembl	F	sphingolipid binding
GO:0038036	IDA:UniProtKB	F	sphingosine-1-phosphate receptor activity
GO:0031532	ISS:UniProtKB	P	actin cytoskeleton reorganization
GO:0007193	IEA:Ensembl	P	adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
GO:0001525	IEA:UniProtKB-KW	P	angiogenesis
GO:0001955	ISS:UniProtKB	P	blood vessel maturation
GO:0007420	IEA:Ensembl	P	brain development
GO:0003245	ISS:UniProtKB	P	cardiac muscle tissue growth involved in heart morphogenesis
GO:0007155	TAS:ProtInc	P	cell adhesion
GO:0016477	ISS:UniProtKB	P	cell migration
GO:0006935	ISS:UniProtKB	P	chemotaxis
GO:0045446	IEA:Ensembl	P	endothelial cell differentiation
GO:0007186	TAS:ProtInc	P	G-protein coupled receptor signaling pathway
GO:0061384	ISS:UniProtKB	P	heart trabecula morphogenesis
GO:0030032	ISS:UniProtKB	P	lamellipodium assembly
GO:0051497	IEA:Ensembl	P	negative regulation of stress fiber assembly
GO:0030182	IEA:Ensembl	P	neuron differentiation
GO:0030335	IEA:Ensembl	P	positive regulation of cell migration
GO:0051482	IEA:Ensembl	P	positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway
GO:0050927	IEA:Ensembl	P	positive regulation of positive chemotaxis
GO:0032320	IEA:Ensembl	P	positive regulation of Ras GTPase activity
GO:0048661	IEA:Ensembl	P	positive regulation of smooth muscle cell proliferation
GO:0045944	IEA:Ensembl	P	positive regulation of transcription from RNA polymerase II promoter
GO:0030500	ISS:UniProtKB	P	regulation of bone mineralization
GO:0045124	ISS:UniProtKB	P	regulation of bone resorption
GO:0030155	IEA:Ensembl	P	regulation of cell adhesion
GO:0003376	IDA:UniProtKB	P	sphingosine-1-phosphate signaling pathway
GO:0072678	ISS:UniProtKB	P	T cell migration
GO:0019226	IEA:Ensembl	P	transmission of nerve impulse

KEGG Pathway Links

KEGG Pathway ID	Description
hsa04068	FoxO signaling pathway

REACTOME Pathway Links

REACTOME Pathway ID	Description
REACT_19231	G alpha (i) signalling events