LMPD Database

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LMP002622

Record overview

LMPD IDLMP002622
Gene ID340485
SpeciesHomo sapiens (Human)
Gene Namealkaline ceramidase 2
Gene SymbolACER2
SynonymsALKCDase2; ASAH3L
Chromosome9
Map Location9p22.1
SummaryThe sphingolipid metabolite sphingosine-1-phosphate promotes cell proliferation and survival, whereas its precursor, sphingosine, has the opposite effect. The ceramidase ACER2 hydrolyzes very long chain ceramides to generate sphingosine (Xu et al., 2006 [PubMed 16940153]).[supplied by OMIM, Jul 2010]
OrthologsView orthologs and multiple alignments for ACER2

Proteins

alkaline ceramidase 2
Refseq ID:NP_001010887
Protein GI:71043498
UniProt ID:Q5QJU3
mRNA ID:NM_001010887
Length:275
RefSeq Status:VALIDATED
MGAPHWWDQLQAGSSEVDWCEDNYTIVPAIAEFYNTISNVLFFILPPICMCLFRQYATCFNSGIYLIWTLLVVVGIGSVYFHATLSFLGQMLDELAVLWV
LMCALAMWFPRRYLPKIFRNDRGRFKVVVSVLSAVTTCLAFVKPAINNISLMTLGVPCTALLIAELKRCDNMRVFKLGLFSGLWWTLALFCWISDRAFCE
LLSSFNFPYLHCMWHILICLAAYLGCVCFAYFDAASEIPEQGPVIKFWPNEKWAFIGVPYVSLLCANKKSSVKIT