LMPD Database

LMP002617

Gene Information

Entrez Gene ID5295
Gene Namephosphoinositide-3-kinase, regulatory subunit 1 (alpha)
Gene SymbolPIK3R1
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005911 IEA:EnsemblCcell-cell junction
GO:0005829 TAS:ReactomeCcytosol
GO:0016020 IDA:UniProtKBCmembrane
GO:0005942 ISS:BHF-UCLCphosphatidylinositol 3-kinase complex
GO:0005943 ISS:UniProtKBCphosphatidylinositol 3-kinase complex, class IA
GO:0005886 TAS:ReactomeCplasma membrane
GO:0043125 IDA:UniProtKBFErbB-3 class receptor binding
GO:0043559 IDA:UniProtKBFinsulin binding
GO:0005159 IPI:UniProtKBFinsulin-like growth factor receptor binding
GO:0005158 IPI:UniProtKBFinsulin receptor binding
GO:0043560 ISS:BHF-UCLFinsulin receptor substrate binding
GO:0005168 IPI:UniProtKBFneurotrophin TRKA receptor binding
GO:0043548 ISS:BHF-UCLFphosphatidylinositol 3-kinase binding
GO:0035014 ISS:UniProtKBFphosphatidylinositol 3-kinase regulator activity
GO:0019903 IPI:UniProtKBFprotein phosphatase binding
GO:0005068 ISS:BHF-UCLFtransmembrane receptor protein tyrosine kinase adaptor activity
GO:0030183 IEA:EnsemblPB cell differentiation
GO:0007596 TAS:ReactomePblood coagulation
GO:0034644 IEA:EnsemblPcellular response to UV
GO:0007173 TAS:ReactomePepidermal growth factor receptor signaling pathway
GO:0008625 IEA:EnsemblPextrinsic apoptotic signaling pathway via death domain receptors
GO:0038095 TAS:ReactomePFc-epsilon receptor signaling pathway
GO:0038096 TAS:ReactomePFc-gamma receptor signaling pathway involved in phagocytosis
GO:0008543 TAS:ReactomePfibroblast growth factor receptor signaling pathway
GO:0060396 IDA:BHF-UCLPgrowth hormone receptor signaling pathway
GO:0045087 TAS:ReactomePinnate immune response
GO:0048009 IPI:UniProtKBPinsulin-like growth factor receptor signaling pathway
GO:0008286 TAS:ReactomePinsulin receptor signaling pathway
GO:0008630 IEA:EnsemblPintrinsic apoptotic signaling pathway in response to DNA damage
GO:0050900 TAS:ReactomePleukocyte migration
GO:0043066 IEA:EnsemblPnegative regulation of apoptotic process
GO:0001953 IEA:EnsemblPnegative regulation of cell-matrix adhesion
GO:0045671 IEA:EnsemblPnegative regulation of osteoclast differentiation
GO:0048011 TAS:ReactomePneurotrophin TRK receptor signaling pathway
GO:0051531 IEA:EnsemblPNFAT protein import into nucleus
GO:0014065 IDA:BHF-UCLPphosphatidylinositol 3-kinase signaling
GO:0006661 TAS:ReactomePphosphatidylinositol biosynthetic process
GO:0048015 TAS:ReactomePphosphatidylinositol-mediated signaling
GO:0046854 ISS:UniProtKBPphosphatidylinositol phosphorylation
GO:0006644 TAS:ReactomePphospholipid metabolic process
GO:0030168 TAS:ReactomePplatelet activation
GO:0030335 IEA:EnsemblPpositive regulation of cell migration
GO:0090004 ISS:BHF-UCLPpositive regulation of establishment of protein localization to plasma membrane
GO:0046326 ISS:BHF-UCLPpositive regulation of glucose import
GO:0045944 IEA:EnsemblPpositive regulation of transcription from RNA polymerase II promoter
GO:0032760 IEA:EnsemblPpositive regulation of tumor necrosis factor production
GO:0006468 IEA:EnsemblPprotein phosphorylation
GO:0043551 ISS:BHF-UCLPregulation of phosphatidylinositol 3-kinase activity
GO:0044281 TAS:ReactomePsmall molecule metabolic process
GO:0031295 TAS:ReactomePT cell costimulation
GO:0050852 TAS:ReactomePT cell receptor signaling pathway
GO:0016032 IEA:UniProtKB-KWPviral process
KEGG Pathway Links
KEGG Pathway IDDescription
hsa04152AMPK signaling pathway
hsa04024cAMP signaling pathway
hsa04022cGMP-PKG signaling pathway
hsa04550Signaling pathways regulating pluripotency of stem cells