LMPD Database

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LMP002609

UniProt Annotations

Entry Information
Gene Namecytochrome P450, family 2. subfamily c, polypeptide 37
Protein EntryCP237_MOUSE
UniProt IDP56654
SpeciesMouse
Comments
Comment typeDescription
Catalytic ActivityRH + reduced flavoprotein + O(2) = ROH + oxidized flavoprotein + H(2)O.
CofactorName=heme; Xref=ChEBI:CHEBI:30413; Evidence={ECO:0000250};
FunctionMetabolizes arachidonic acid to produce 12- hydroxyeicosatetraenoic acid (HETE).
InductionP450 can be induced to high levels in liver and other tissues by various foreign compounds, including drugs, pesticides, and carcinogens.
SimilarityBelongs to the cytochrome P450 family. {ECO:0000305}.
Subcellular LocationEndoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Tissue SpecificityLiver.