LMPD Database

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LMP002538

UniProt Annotations

Entry Information
Gene Namealcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
Protein EntryADH7_MOUSE
UniProt IDQ64437
SpeciesMouse
Comments
Comment typeDescription
Catalytic ActivityAn alcohol + NAD(+) = an aldehyde or ketone + NADH.
CofactorName=Zn(2+); Xref=ChEBI:CHEBI:29105; Evidence={ECO:0000250}; Note=Binds 2 Zn(2+) ions per subunit. {ECO:0000250};
FunctionCould function in retinol oxidation for the synthesis of retinoic acid, a hormone important for cellular differentiation.
SimilarityBelongs to the zinc-containing alcohol dehydrogenase family. Class-IV subfamily. {ECO:0000305}.
Subcellular LocationCytoplasm.
SubunitHomodimer.
Tissue SpecificityHigh expression in the stomach mucosa. Lower expression in eye, thymus, skin and ovary. Very low expression in small intestine, liver and uterus.