LMPD Database

LMP002387

Gene Information

Entrez Gene ID	2923
Gene Name	protein disulfide isomerase family A, member 3
Gene Symbol	PDIA3
Species	Homo sapiens

Gene Ontology (GO Annotations)

GO ID	Source	Type	Description
GO:0009986	IDA:MGI	C	cell surface
GO:0005783	IDA:UniProtKB	C	endoplasmic reticulum
GO:0005788	TAS:Reactome	C	endoplasmic reticulum lumen
GO:0070062	IDA:UniProt	C	extracellular vesicular exosome
GO:0005925	IDA:UniProtKB	C	focal adhesion
GO:0005634	IDA:UniProt	C	nucleus
GO:0004197	TAS:ProtInc	F	cysteine-type endopeptidase activity
GO:0004629	TAS:ProtInc	F	phospholipase C activity
GO:0044822	IDA:UniProtKB	F	poly(A) RNA binding
GO:0003756	IBA:RefGenome	F	protein disulfide isomerase activity
GO:0042590	TAS:Reactome	P	antigen processing and presentation of exogenous peptide antigen via MHC class I
GO:0002479	TAS:Reactome	P	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
GO:0002474	TAS:Reactome	P	antigen processing and presentation of peptide antigen via MHC class I
GO:0045454	IEA:InterPro	P	cell redox homeostasis
GO:0044267	TAS:Reactome	P	cellular protein metabolic process
GO:2001238	IEA:Ensembl	P	positive regulation of extrinsic apoptotic signaling pathway
GO:0043687	TAS:Reactome	P	post-translational protein modification
GO:0006457	IBA:RefGenome	P	protein folding
GO:0006606	TAS:ProtInc	P	protein import into nucleus
GO:0018279	TAS:Reactome	P	protein N-linked glycosylation via asparagine
GO:0006621	TAS:ProtInc	P	protein retention in ER lumen
GO:0006508	TAS:GOC	P	proteolysis
GO:0034976	IBA:RefGenome	P	response to endoplasmic reticulum stress
GO:0007165	TAS:ProtInc	P	signal transduction

KEGG Pathway Links

KEGG Pathway ID	Description
hsa04612	Antigen processing and presentation
hsa04141	Protein processing in endoplasmic reticulum

REACTOME Pathway Links

REACTOME Pathway ID	Description
REACT_75795	Antigen Presentation: Folding, assembly and peptide loading of class I MHC
REACT_111178	ER-Phagosome pathway