LMPD Database

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LMP002369

UniProt Annotations

Entry Information
Gene Nameglycerophosphodiester phosphodiesterase 1
Protein EntryGDE1_HUMAN
UniProt IDQ9NZC3
SpeciesHuman
Comments
Comment typeDescription
Catalytic Activity1-(sn-glycero-3-phospho)-1D-myo-inositol + H(2)O = myo-inositol + sn-glycerol 3-phosphate.
CofactorName=Mg(2+); Xref=ChEBI
FunctionHas glycerophosphoinositol phosphodiesterase activity. Has little or no activity towards glycerophosphocholine. GDE1 activity can be modulated by G-protein signaling pathways (By similarity).
PtmN-glycosylated.
Sequence CautionSequence=AAC05440.1; Type=Erroneous gene model prediction; Evidence= ; Sequence=AAC05803.1; Type=Erroneous gene model prediction; Evidence= ;
SimilarityBelongs to the glycerophosphoryl diester phosphodiesterase family.
SimilarityContains 1 GP-PDE domain.
Subcellular LocationCytoplasm . Membrane {ECO
SubunitInteracts with RGS16 (By similarity). Interacts with PRAF2.
Tissue SpecificityWidely expressed.