LMPD Database

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LMP002282

Gene Information

Entrez Gene ID20423
Gene Namesonic hedgehog
Gene SymbolShh
SpeciesMus musculus
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0009986 IDA:MGICcell surface
GO:0031012 IDA:MGICextracellular matrix
GO:0005615 IDA:MGICextracellular space
GO:0016020 IDA:MGICmembrane
GO:0045121 IDA:MGICmembrane raft
GO:0005634 IDA:MGICnucleus
GO:0005886 IEA:UniProtKB-KWCplasma membrane
GO:0005509 ISS:UniProtKBFcalcium ion binding
GO:0001948 IDA:MGIFglycoprotein binding
GO:0005539 IDA:MGIFglycosaminoglycan binding
GO:0043237 IDA:MGIFlaminin-1 binding
GO:0005113 IPI:BHF-UCLFpatched binding
GO:0008270 ISS:UniProtKBFzinc ion binding
GO:0048856 IMP:MGIPanatomical structure development
GO:0048646 IMP:MGIPanatomical structure formation involved in morphogenesis
GO:0008209 IMP:MGIPandrogen metabolic process
GO:0001525 IDA:MGIPangiogenesis
GO:0009952 IMP:MGIPanterior/posterior pattern specification
GO:0006915 IGI:MGIPapoptotic process
GO:0097190 IDA:RoslinPapoptotic signaling pathway
GO:0060840 IMP:MGIPartery development
GO:0007411 IDA:MGIPaxon guidance
GO:0060020 IDA:MGIPBergmann glial cell differentiation
GO:0007596 IMP:MGIPblood coagulation
GO:0060442 IDA:MGIPbranching involved in prostate gland morphogenesis
GO:0060445 IMP:MGIPbranching involved in salivary gland morphogenesis
GO:0001658 IMP:MGIPbranching involved in ureteric bud morphogenesis
GO:0048754 IMP:MGIPbranching morphogenesis of an epithelial tube
GO:0060447 IMP:MGIPbud outgrowth involved in lung branching
GO:0043010 IDA:MGIPcamera-type eye development
GO:0060070 IDA:MGIPcanonical Wnt signaling pathway
GO:0043369 IMP:BHF-UCLPCD4-positive or CD8-positive, alpha-beta T cell lineage commitment
GO:0007267 IMP:MGIPcell-cell signaling
GO:0048468 IMP:MGIPcell development
GO:0045165 IGI:MGIPcell fate commitment
GO:0001708 IDA:MGIPcell fate specification
GO:0008283 IGI:MGIPcell proliferation
GO:0071285 IDA:MGIPcellular response to lithium ion
GO:0007417 IMP:MGIPcentral nervous system development
GO:0021930 IGI:UniProtKBPcerebellar granule cell precursor proliferation
GO:0003140 IMP:BHF-UCLPdetermination of left/right asymmetry in lateral mesoderm
GO:0007368 IMP:MGIPdetermination of left/right symmetry
GO:0048589 IMP:MGIPdevelopmental growth
GO:0048546 IMP:MGIPdigestive tract morphogenesis
GO:0021904 IMP:BHF-UCLPdorsal/ventral neural tube patterning
GO:0009953 IGI:MGIPdorsal/ventral pattern formation
GO:0007398 IMP:MGIPectoderm development
GO:0048557 TAS:BHF-UCLPembryonic digestive tract morphogenesis
GO:0042733 IMP:RoslinPembryonic digit morphogenesis
GO:0048617 IMP:MGIPembryonic foregut morphogenesis
GO:0035115 IMP:MGIPembryonic forelimb morphogenesis
GO:0035116 IMP:MGIPembryonic hindlimb morphogenesis
GO:0030326 IMP:MGIPembryonic limb morphogenesis
GO:0048598 IMP:MGIPembryonic morphogenesis
GO:0048568 IMP:MGIPembryonic organ development
GO:0048706 IGI:MGIPembryonic skeletal system development
GO:0006897 IDA:MGIPendocytosis
GO:0060664 IMP:MGIPepithelial cell proliferation involved in salivary gland morphogenesis
GO:0060684 IMP:MGIPepithelial-mesenchymal cell signaling
GO:0060738 IGI:MGIPepithelial-mesenchymal signaling involved in prostate gland development
GO:0060441 IMP:MGIPepithelial tube branching involved in lung morphogenesis
GO:0030010 IDA:MGIPestablishment of cell polarity
GO:0030900 IGI:MGIPforebrain development
GO:0048859 IMP:MGIPformation of anatomical boundary
GO:0001942 IMP:MGIPhair follicle development
GO:0031069 IMP:MGIPhair follicle morphogenesis
GO:0007507 IMP:MGIPheart development
GO:0001947 IMP:BHF-UCLPheart looping
GO:0030902 IMP:MGIPhindbrain development
GO:0007442 IMP:MGIPhindgut morphogenesis
GO:0048839 IMP:MGIPinner ear development
GO:0016539 IEA:InterProPintein-mediated protein splicing
GO:0045109 IMP:MGIPintermediate filament organization
GO:0001822 IMP:MGIPkidney development
GO:0060459 IMP:MGIPleft lung development
GO:0060174 IMP:MGIPlimb bud formation
GO:0060173 IMP:MGIPlimb development
GO:0060484 IMP:MGIPlung-associated mesenchyme development
GO:0030324 IMP:MGIPlung development
GO:0060428 IMP:MGIPlung epithelium development
GO:0060463 IMP:MGIPlung lobe morphogenesis
GO:0060425 IMP:MGIPlung morphogenesis
GO:0002320 IMP:BHF-UCLPlymphoid progenitor cell differentiation
GO:0030539 IMP:MGIPmale genitalia development
GO:0010463 IMP:MGIPmesenchymal cell proliferation
GO:0060916 IDA:MGIPmesenchymal cell proliferation involved in lung development
GO:0060783 IMP:MGIPmesenchymal smoothened signaling pathway involved in prostate gland development
GO:0072136 IMP:UniProtKBPmetanephric mesenchymal cell proliferation involved in metanephros development
GO:0001656 IMP:UniProtKBPmetanephros development
GO:0030901 IGI:MGIPmidbrain development
GO:0080125 IMP:MGIPmulticellular structure septum development
GO:0045445 IDA:MGIPmyoblast differentiation
GO:0014902 IMP:MGIPmyotube differentiation
GO:0046639 IMP:MGIPnegative regulation of alpha-beta T cell differentiation
GO:0043066 IDA:RoslinPnegative regulation of apoptotic process
GO:0090090 IMP:MGIPnegative regulation of canonical Wnt signaling pathway
GO:0045596 IDA:MGIPnegative regulation of cell differentiation
GO:0030336 IDA:MGIPnegative regulation of cell migration
GO:0090370 IMP:BHF-UCLPnegative regulation of cholesterol efflux
GO:0010629 IMP:UniProtKBPnegative regulation of gene expression
GO:2000357 IDA:UniProtKBPnegative regulation of kidney smooth muscle cell differentiation
GO:2001054 IMP:MGIPnegative regulation of mesenchymal cell apoptotic process
GO:0032435 IMP:MGIPnegative regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0042177 IMP:MGIPnegative regulation of protein catabolic process
GO:0042130 IMP:MGIPnegative regulation of T cell proliferation
GO:0034244 IDA:MGIPnegative regulation of transcription elongation from RNA polymerase II promoter
GO:0000122 IMP:BHF-UCLPnegative regulation of transcription from RNA polymerase II promoter
GO:2000062 IDA:UniProtKBPnegative regulation of ureter smooth muscle cell differentiation
GO:0030178 IDA:MGIPnegative regulation of Wnt signaling pathway
GO:0045060 IMP:BHF-UCLPnegative thymic T cell selection
GO:0001755 IMP:MGIPneural crest cell migration
GO:0007405 IDA:MGIPneuroblast proliferation
GO:0048663 IMP:MGIPneuron fate commitment
GO:0042476 IDA:MGIPodontogenesis
GO:0042475 IMP:MGIPodontogenesis of dentin-containing tooth
GO:0014003 IDA:MGIPoligodendrocyte development
GO:0048709 IGI:MGIPoligodendrocyte differentiation
GO:0048645 IMP:MGIPorgan formation
GO:0002076 IDA:MGIPosteoblast development
GO:0060021 IMP:MGIPpalate development
GO:0031016 IMP:MGIPpancreas development
GO:0001569 IMP:MGIPpatterning of blood vessels
GO:0007389 IMP:MGIPpattern specification process
GO:0009949 IMP:RoslinPpolarity specification of anterior/posterior axis
GO:0046638 IMP:BHF-UCLPpositive regulation of alpha-beta T cell differentiation
GO:0045597 IMP:MGIPpositive regulation of cell differentiation
GO:0051781 IEA:EnsemblPpositive regulation of cell division
GO:0008284 IDA:MGIPpositive regulation of cell proliferation
GO:0021940 IDA:MGIPpositive regulation of cerebellar granule cell precursor proliferation
GO:0060769 IMP:MGIPpositive regulation of epithelial cell proliferation involved in prostate gland development
GO:0010628 IMP:UniProtKBPpositive regulation of gene expression
GO:0007228 IMP:BHF-UCLPpositive regulation of hh target transcription factor activity
GO:0033092 IMP:BHF-UCLPpositive regulation of immature T cell proliferation in thymus
GO:2000358 IDA:UniProtKBPpositive regulation of kidney smooth muscle cell differentiation
GO:0002053 IMP:MGIPpositive regulation of mesenchymal cell proliferation
GO:2000729 IMP:UniProtKBPpositive regulation of mesenchymal cell proliferation involved in ureter development
GO:0002052 IDA:MGIPpositive regulation of neuroblast proliferation
GO:0048714 IDA:MGIPpositive regulation of oligodendrocyte differentiation
GO:0042307 IGI:MGIPpositive regulation of protein import into nucleus
GO:0061189 IEA:EnsemblPpositive regulation of sclerotome development
GO:0014858 IMP:MGIPpositive regulation of skeletal muscle cell proliferation
GO:0048643 IMP:MGIPpositive regulation of skeletal muscle tissue development
GO:0045880 ISS:UniProtKBPpositive regulation of smoothened signaling pathway
GO:0051155 IMP:MGIPpositive regulation of striated muscle cell differentiation
GO:0033089 IMP:BHF-UCLPpositive regulation of T cell differentiation in thymus
GO:0045893 IDA:UniProtKBPpositive regulation of transcription, DNA-templated
GO:0045944 IDA:BHF-UCLPpositive regulation of transcription from RNA polymerase II promoter
GO:2000063 IMP:UniProtKBPpositive regulation of ureter smooth muscle cell differentiation
GO:0030177 IMP:MGIPpositive regulation of Wnt signaling pathway
GO:0045059 IMP:BHF-UCLPpositive thymic T cell selection
GO:0060516 IDA:MGIPprimary prostatic bud elongation
GO:0060523 IDA:MGIPprostate epithelial cord elongation
GO:0030850 IMP:MGIPprostate gland development
GO:0034504 IDA:MGIPprotein localization to nucleus
GO:0006508 IEA:UniProtKB-KWPproteolysis
GO:0042127 IDA:MGIPregulation of cell proliferation
GO:0060768 IMP:MGIPregulation of epithelial cell proliferation involved in prostate gland development
GO:0010468 IDA:MGIPregulation of gene expression
GO:0060782 IMP:MGIPregulation of mesenchymal cell proliferation involved in prostate gland development
GO:0042481 IMP:BHF-UCLPregulation of odontogenesis
GO:0060685 IDA:MGIPregulation of prostatic bud formation
GO:0030162 IDA:MGIPregulation of proteolysis
GO:0006355 IMP:MGIPregulation of transcription, DNA-templated
GO:0030323 IMP:MGIPrespiratory tube development
GO:0060458 IMP:MGIPright lung development
GO:0060662 IDA:MGIPsalivary gland cavitation
GO:0007165 TAS:MGIPsignal transduction
GO:0043588 IMP:MGIPskin development
GO:0007224 IDA:MGIPsmoothened signaling pathway
GO:0021938 IDA:MGIPsmoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation
GO:0061053 IMP:BHF-UCLPsomite development
GO:0021513 IMP:MGIPspinal cord dorsal/ventral patterning
GO:0021522 IGI:MGIPspinal cord motor neuron differentiation
GO:0048864 IMP:BHF-UCLPstem cell development
GO:0051146 IDA:MGIPstriated muscle cell differentiation
GO:0014706 IMP:MGIPstriated muscle tissue development
GO:0033077 IMP:BHF-UCLPT cell differentiation in thymus
GO:0021978 IMP:MGIPtelencephalon regionalization
GO:0021794 IMP:MGIPthalamus development
GO:0048538 IMP:BHF-UCLPthymus development
GO:0030878 IMP:MGIPthyroid gland development
GO:0060438 IMP:MGIPtrachea development
GO:0060439 IMP:MGIPtrachea morphogenesis
GO:0001944 IMP:MGIPvasculature development
GO:0001570 IDA:MGIPvasculogenesis
GO:0060979 TAS:DFLATPvasculogenesis involved in coronary vascular morphogenesis
KEGG Pathway Links
KEGG Pathway IDDescription
mmu05217Basal cell carcinoma