LMPD Database

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LMP002259

Gene Information

Entrez Gene ID5335
Gene Namephospholipase C, gamma 1
Gene SymbolPLCG1
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005911 IEA:EnsemblCcell-cell junction
GO:0042995 IDA:BHF-UCLCcell projection
GO:0008180 IDA:UniProtKBCCOP9 signalosome
GO:0005737 IDA:MGICcytoplasm
GO:0005829 IDA:UniProtKBCcytosol
GO:0030027 IDA:UniProtKBClamellipodium
GO:0005886 IDA:UniProtKBCplasma membrane
GO:0001726 IDA:UniProtKBCruffle
GO:0005509 IEA:InterProFcalcium ion binding
GO:0005168 IPI:UniProtKBFneurotrophin TRKA receptor binding
GO:0004435 IDA:UniProtKBFphosphatidylinositol phospholipase C activity
GO:0004629 TAS:ReactomeFphospholipase C activity
GO:0019901 IPI:BHF-UCLFprotein kinase binding
GO:0005057 NAS:UniProtKBFreceptor signaling protein activity
GO:0000186 TAS:ReactomePactivation of MAPKK activity
GO:0007202 TAS:ReactomePactivation of phospholipase C activity
GO:0007411 TAS:ReactomePaxon guidance
GO:0007596 TAS:ReactomePblood coagulation
GO:0019722 IMP:BHF-UCLPcalcium-mediated signaling
GO:0016477 IMP:BHF-UCLPcell migration
GO:0071364 IDA:UniProtKBPcellular response to epidermal growth factor stimulus
GO:0019221 TAS:ReactomePcytokine-mediated signaling pathway
GO:0007173 IMP:BHF-UCLPepidermal growth factor receptor signaling pathway
GO:0038095 TAS:ReactomePFc-epsilon receptor signaling pathway
GO:0038096 TAS:ReactomePFc-gamma receptor signaling pathway involved in phagocytosis
GO:0008543 TAS:ReactomePfibroblast growth factor receptor signaling pathway
GO:0045087 TAS:ReactomePinnate immune response
GO:0043647 TAS:ReactomePinositol phosphate metabolic process
GO:0001701 IEA:EnsemblPin utero embryonic development
GO:0050900 TAS:ReactomePleukocyte migration
GO:0048011 TAS:ReactomePneurotrophin TRK receptor signaling pathway
GO:0009395 IEA:InterProPphospholipid catabolic process
GO:0045766 IDA:DFLATPpositive regulation of angiogenesis
GO:0043536 IDA:DFLATPpositive regulation of blood vessel endothelial cell migration
GO:0010634 IMP:UniProtKBPpositive regulation of epithelial cell migration
GO:0051281 IMP:BHF-UCLPpositive regulation of release of sequestered calcium ion into cytosol
GO:0007165 NAS:UniProtKBPsignal transduction
GO:0044281 TAS:ReactomePsmall molecule metabolic process
GO:0050852 TAS:ReactomePT cell receptor signaling pathway
GO:0016032 IEA:UniProtKB-KWPviral process
KEGG Pathway Links
KEGG Pathway IDDescription
hsa04750Inflammatory mediator regulation of TRP channels
hsa04015Rap1 signaling pathway
hsa04014Ras signaling pathway
hsa04919Thyroid hormone signaling pathway