LMPD Database

LMP002248

UniProt Annotations

Entry Information
Gene Namealcohol dehydrogenase 1 (class I)
Protein EntryADH1_MOUSE
UniProt IDP00329
SpeciesMouse
Comments
Comment typeDescription
Catalytic ActivityAn alcohol + NAD(+) = an aldehyde or ketone + NADH.
CofactorName=Zn(2+); Xref=ChEBI:CHEBI:29105; Note=Binds 2 Zn(2+) ions per subunit.;
SimilarityBelongs to the zinc-containing alcohol dehydrogenase family. Class-I subfamily. {ECO:0000305}.
Subcellular LocationCytoplasm.
SubunitDimer of identical or non-identical chains of three types (A, B, C), which are coded by 3 separate genes at different loci.
Tissue SpecificityExpressed at high levels in the liver, small intestine and eye, at moderate levels in kidney, ovary and uterus, and at low levels in the spinal cord, thymus, heart, stomach mucosa, skin and testis. {ECO:0000269|PubMed:7738026}.