LMPD Database

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LMP002242

UniProt Annotations

Entry Information
Gene Nameceramide synthase 6
Protein EntryCERS6_MOUSE
UniProt IDQ8C172
SpeciesMouse
Comments
Comment typeDescription
FunctionMay be involved in sphingolipid synthesis or its regulation. {ECO:0000269|PubMed:15823095}.
PtmGlycosylation on Asn-18 is not necessary for function. {ECO:0000269|PubMed:15823095}.
SimilarityContains 1 homeobox DNA-binding domain. {ECO:0000255|PROSITE-ProRule:PRU00108}.
SimilarityContains 1 TLC (TRAM/LAG1/CLN8) domain. {ECO:0000255|PROSITE-ProRule:PRU00205}.
Subcellular LocationNucleus membrane {ECO:0000255|PROSITE- ProRule:PRU00108}; Multi-pass membrane protein {ECO:0000305}. Endoplasmic reticulum membrane {ECO:0000269|PubMed:15823095}; Multi-pass membrane protein {ECO:0000269|PubMed:15823095}.
Tissue SpecificityBroadly expressed, with highest levels in kidney and brain. {ECO:0000269|PubMed:15823095}.