LMPD Database

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LMP002238

UniProt Annotations

Entry Information
Gene Nameinositol hexaphosphate kinase 1
Protein EntryIP6K1_MOUSE
UniProt IDQ6PD10
SpeciesMouse
Comments
Comment typeDescription
Catalytic ActivityATP + 1D-myo-inositol 1-diphosphate 2,3,4,5,6- pentakisphosphate = ADP + 1D-myo-inositol 1,5-bis(diphosphate) 2,3,4,6-tetrakisphosphate.
Catalytic ActivityATP + 1D-myo-inositol hexakisphosphate = ADP + 1D-myo-inositol 5-diphosphate 1,2,3,4,6-pentakisphosphate.
FunctionConverts inositol hexakisphosphate (InsP6) to diphosphoinositol pentakisphosphate (InsP7/PP-InsP5). Converts 1,3,4,5,6-pentakisphosphate (InsP5) to PP-InsP4. {ECO:0000269|PubMed:10574768}.
SimilarityBelongs to the inositol phosphokinase (IPK) family. {ECO:0000305}.
Subcellular LocationCytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.
Tissue SpecificityHighly expressed in brain and testis. Detected at much lower levels in heart, kidney, liver, lung and spleen. {ECO:0000269|PubMed:10574768}.