LMPD Database

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LMP002227

Gene Information

Entrez Gene ID18708
Gene Namephosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)
Gene SymbolPik3r1
SpeciesMus musculus
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005911 IDA:MGICcell-cell junction
GO:0005737 IDA:UniProtKBCcytoplasm
GO:0005829 IDA:UniProtKBCcytosol
GO:0016020 IDA:UniProtKBCmembrane
GO:0005942 TAS:MGICphosphatidylinositol 3-kinase complex
GO:0005943 ISS:UniProtKBCphosphatidylinositol 3-kinase complex, class IA
GO:0016303 TAS:MGIF1-phosphatidylinositol-3-kinase activity
GO:0043125 ISS:UniProtKBFErbB-3 class receptor binding
GO:0043559 IEA:EnsemblFinsulin binding
GO:0005159 ISS:UniProtKBFinsulin-like growth factor receptor binding
GO:0005158 ISS:UniProtKBFinsulin receptor binding
GO:0043560 IPI:UniProtKBFinsulin receptor substrate binding
GO:0035014 ISS:UniProtKBFphosphatidylinositol 3-kinase regulator activity
GO:0030183 IMP:MGIPB cell differentiation
GO:0034644 IMP:MGIPcellular response to UV
GO:0008625 IMP:MGIPextrinsic apoptotic signaling pathway via death domain receptors
GO:0060396 IEA:EnsemblPgrowth hormone receptor signaling pathway
GO:0048009 ISS:UniProtKBPinsulin-like growth factor receptor signaling pathway
GO:0008286 ISS:UniProtKBPinsulin receptor signaling pathway
GO:0008630 IMP:MGIPintrinsic apoptotic signaling pathway in response to DNA damage
GO:0043066 IDA:MGIPnegative regulation of apoptotic process
GO:0001953 IGI:MGIPnegative regulation of cell-matrix adhesion
GO:0045671 IGI:MGIPnegative regulation of osteoclast differentiation
GO:0051531 IMP:MGIPNFAT protein import into nucleus
GO:0014065 IEA:EnsemblPphosphatidylinositol 3-kinase signaling
GO:0036092 TAS:GOCPphosphatidylinositol-3-phosphate biosynthetic process
GO:0046854 ISS:UniProtKBPphosphatidylinositol phosphorylation
GO:0030335 IGI:MGIPpositive regulation of cell migration
GO:0045944 IMP:MGIPpositive regulation of transcription from RNA polymerase II promoter
GO:0032760 IMP:MGIPpositive regulation of tumor necrosis factor production
GO:0006468 IDA:MGIPprotein phosphorylation
GO:0043551 ISS:GOCPregulation of phosphatidylinositol 3-kinase activity
KEGG Pathway Links
KEGG Pathway IDDescription
mmu04152AMPK signaling pathway
mmu04024cAMP signaling pathway
mmu04022cGMP-PKG signaling pathway
mmu04550Signaling pathways regulating pluripotency of stem cells