LMPD Database

LMP002225

UniProt Annotations

Entry Information
Gene Namesolute carrier family 10, member 4
Protein EntryNTCP4_HUMAN
UniProt IDQ96EP9
SpeciesHuman
Comments
Comment typeDescription
FunctionTransporter for bile acids.
PtmActivated following N-terminal proteolytic cleavage by thrombin and/or proteases.
SimilarityBelongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.
Subcellular LocationCell membrane ; Multi-pass membrane protein .
Tissue SpecificityHighly expressed in brain and small intestine, and moderately expressed in colon, heart, prostate, and testis. Very low levels were detected in kidney, liver, ovary, placenta, spleen, and thymus.