LMPD Database

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LMP002218

UniProt Annotations

Entry Information
Gene Nameacyl-Coenzyme A dehydrogenase family, member 8
Protein EntryACAD8_MOUSE
UniProt IDQ9D7B6
SpeciesMouse
Comments
Comment typeDescription
Catalytic ActivityIsobutyryl-CoA + ETF = methylacrylyl-CoA + reduced ETF.
CofactorName=FAD; Xref=ChEBI:CHEBI:57692; Evidence={ECO:0000250};
FunctionHas very high activity toward isobutyryl-CoA. Is an isobutyryl-CoA dehydrogenase that functions in valine catabolism (By similarity). {ECO:0000250}.
PathwayAmino-acid degradation; L-valine degradation.
Sequence CautionSequence=BAC26664.1; Type=Erroneous initiation; Evidence={ECO:0000305};
SimilarityBelongs to the acyl-CoA dehydrogenase family. {ECO:0000305}.
Subcellular LocationMitochondrion {ECO:0000250}.
SubunitHomotetramer, formed by a dimer of dimers. Subunit of the large multiprotein complex ARC/DRIP (By similarity). {ECO:0000250}.