LMPD Database

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LMP002214

UniProt Annotations

Entry Information
Gene Namesteroidogenic acute regulatory protein
Protein EntrySTAR_MOUSE
UniProt IDP51557
SpeciesMouse
Comments
Comment typeDescription
FunctionPlays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Transporter that binds to and transport cholesterol through the intermembrane space of the mitochondrion (Probable). {ECO:0000305}.
PathwaySteroid metabolism; cholesterol metabolism.
SimilarityContains 1 START domain. {ECO:0000255|PROSITE- ProRule:PRU00197}.
Subcellular LocationMitochondrion {ECO:0000269|PubMed:7588255}.
SubunitMay interact with TSPO. {ECO:0000250}.
Tissue SpecificityExpressed within glia and neurons in discrete regions of the brain. {ECO:0000269|PubMed:12486153}.