LMPD Database

LMP002189

Gene Information

Entrez Gene ID	5584
Gene Name	protein kinase C, iota
Gene Symbol	PRKCI
Species	Homo sapiens

Gene Ontology (GO Annotations)

GO ID	Source	Type	Description
GO:0016324	IEA:Ensembl	C	apical plasma membrane
GO:0031252	IEA:Ensembl	C	cell leading edge
GO:0005737	IDA:HPA	C	cytoplasm
GO:0005829	IDA:UniProtKB	C	cytosol
GO:0005768	IEA:UniProtKB-KW	C	endosome
GO:0070062	IDA:UniProt	C	extracellular vesicular exosome
GO:0000139	IEA:GOC	C	Golgi membrane
GO:0045171	IDA:HPA	C	intercellular bridge
GO:0015630	IDA:HPA	C	microtubule cytoskeleton
GO:0005634	IDA:UniProtKB	C	nucleus
GO:0005886	TAS:Reactome	C	plasma membrane
GO:0043234	IEA:Ensembl	C	protein complex
GO:0043220	IEA:Ensembl	C	Schmidt-Lanterman incisure
GO:0005524	TAS:UniProtKB	F	ATP binding
GO:0005543	IDA:UniProtKB	F	phospholipid binding
GO:0004672	IDA:UniProtKB	F	protein kinase activity
GO:0004697	ISS:BHF-UCL	F	protein kinase C activity
GO:0004674	IDA:UniProtKB	F	protein serine/threonine kinase activity
GO:0008270	IEA:InterPro	F	zinc ion binding
GO:0007015	IEA:Ensembl	P	actin filament organization
GO:0045216	IMP:UniProtKB	P	cell-cell junction organization
GO:0034329	TAS:Reactome	P	cell junction assembly
GO:0016477	IEA:Ensembl	P	cell migration
GO:0032869	ISS:BHF-UCL	P	cellular response to insulin stimulus
GO:0007010	NAS:UniProtKB	P	cytoskeleton organization
GO:0035089	IEA:Ensembl	P	establishment of apical/basal cell polarity
GO:0045197	TAS:UniProtKB	P	establishment or maintenance of epithelial cell apical/basal polarity
GO:0042462	IEA:Ensembl	P	eye photoreceptor cell development
GO:0048194	IEA:Ensembl	P	Golgi vesicle budding
GO:0035556	IEA:InterPro	P	intracellular signal transduction
GO:0061024	NAS:UniProtKB	P	membrane organization
GO:0043066	TAS:Reactome	P	negative regulation of apoptotic process
GO:0034351	IMP:UniProtKB	P	negative regulation of glial cell apoptotic process
GO:0043524	IDA:UniProtKB	P	negative regulation of neuron apoptotic process
GO:0048011	TAS:Reactome	P	neurotrophin TRK receptor signaling pathway
GO:2000353	IMP:UniProtKB	P	positive regulation of endothelial cell apoptotic process
GO:0090004	ISS:BHF-UCL	P	positive regulation of establishment of protein localization to plasma membrane
GO:0060252	IMP:UniProtKB	P	positive regulation of glial cell proliferation
GO:0046326	ISS:BHF-UCL	P	positive regulation of glucose import
GO:0010976	IMP:UniProtKB	P	positive regulation of neuron projection development
GO:0051092	IDA:UniProtKB	P	positive regulation of NF-kappaB transcription factor activity
GO:0006468	IDA:UniProtKB	P	protein phosphorylation
GO:0006612	NAS:UniProtKB	P	protein targeting to membrane
GO:0070555	IEA:Ensembl	P	response to interleukin-1
GO:0046903	NAS:UniProtKB	P	secretion
GO:0070830	TAS:Reactome	P	tight junction assembly
GO:0016192	TAS:UniProtKB	P	vesicle-mediated transport

KEGG Pathway Links

KEGG Pathway ID	Description
hsa04390	Hippo signaling pathway
hsa04611	Platelet activation
hsa04015	Rap1 signaling pathway