LMPD Database

LMP002149

Gene Information

Entrez Gene ID	200576
Gene Name	phosphoinositide kinase, FYVE finger containing
Gene Symbol	PIKFYVE
Species	Homo sapiens

Gene Ontology (GO Annotations)

GO ID	Source	Type	Description
GO:0005911	IEA:Ensembl	C	cell-cell junction
GO:0031410	IEA:Ensembl	C	cytoplasmic vesicle
GO:0005829	IEA:Ensembl	C	cytosol
GO:0031901	IDA:UniProtKB	C	early endosome membrane
GO:0010008	IDA:UniProtKB	C	endosome membrane
GO:0000139	TAS:Reactome	C	Golgi membrane
GO:0031902	TAS:Reactome	C	late endosome membrane
GO:0045121	IDA:HGNC	C	membrane raft
GO:0048471	IEA:Ensembl	C	perinuclear region of cytoplasm
GO:0012506	IEA:Ensembl	C	vesicle membrane
GO:0000285	IEA:UniProtKB-EC	F	1-phosphatidylinositol-3-phosphate 5-kinase activity
GO:0016308	TAS:HGNC	F	1-phosphatidylinositol-4-phosphate 5-kinase activity
GO:0005524	IEA:UniProtKB-KW	F	ATP binding
GO:0043813	TAS:Reactome	F	phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity
GO:0008270	IEA:Ensembl	F	zinc ion binding
GO:0044267	IEA:InterPro	P	cellular protein metabolic process
GO:0035556	IEA:Ensembl	P	intracellular signal transduction
GO:0032288	IEA:Ensembl	P	myelin assembly
GO:0036092	TAS:GOC	P	phosphatidylinositol-3-phosphate biosynthetic process
GO:0006661	TAS:Reactome	P	phosphatidylinositol biosynthetic process
GO:0046854	TAS:GOC	P	phosphatidylinositol phosphorylation
GO:0006644	TAS:Reactome	P	phospholipid metabolic process
GO:0034504	IMP:UniProtKB	P	protein localization to nucleus
GO:0042147	IMP:UniProtKB	P	retrograde transport, endosome to Golgi
GO:0044281	TAS:Reactome	P	small molecule metabolic process

KEGG Pathway Links

KEGG Pathway ID	Description
hsa04145	Phagosome

REACTOME Pathway Links

REACTOME Pathway ID	Description
REACT_120756	Synthesis of PIPs at the early endosome membrane
REACT_120836	Synthesis of PIPs at the Golgi membrane
REACT_120918	Synthesis of PIPs at the late endosome membrane