LMPD Database

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LMP002077

UniProt Annotations

Entry Information
Gene Namephosphatidylinositol-5-phosphate 4-kinase, type II, gamma
Protein EntryPI42C_HUMAN
UniProt IDQ8TBX8
SpeciesHuman
Comments
Comment typeDescription
Alternative ProductsEvent=Alternative splicing; Named isoforms=3; Name=1; IsoId=Q8TBX8-1; Sequence=Displayed; Name=2; IsoId=Q8TBX8-2; Sequence=VSP_042929; Note=No experimental confirmation available.; Name=3; IsoId=Q8TBX8-3; Sequence=VSP_043369; Note=No experimental confirmation available.;
Catalytic ActivityATP + 1-phosphatidyl-1D-myo-inositol 5- phosphate = ADP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate.
FunctionMay play an important role in the production of Phosphatidylinositol bisphosphate (PIP2), in the endoplasmic reticulum.
InteractionSelf; NbExp=2; IntAct=EBI-1383637, EBI-1383637;
Sequence CautionSequence=BAB15223.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence= ;
SimilarityContains 1 PIPK domain. {ECO
Subcellular LocationCytoplasm. Membrane. Note=Mostly found in the cytosol and surrounding plasma membrane. However, its presence in the endoplasmic reticulum seems to be a prerequisite for PIP2 synthesis (By similarity).