LMPD Database

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LMP002068

UniProt Annotations

Entry Information
Gene NameNADH dehydrogenase, subunit 5 (complex I)
Protein EntryU5ZC31_HUMAN
UniProt IDU5ZC31
SpeciesHuman
Comments
Comment typeDescription
Catalytic ActivityNADH + ubiquinone + 5 H(+)(In) = NAD(+) + ubiquinol + 4 H(+)(Out). {ECO:0000256|RuleBase:RU003404, ECO:0000256|SAAS:SAAS00061104}.
FunctionCore subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone
SimilarityBelongs to the complex I subunit 5 family
Subcellular LocationMitochondrion inner membrane ; Multi-pass membrane protein {ECO:0000256|RuleBase:RU003404, ECO:0000256|SAAS:SAAS00061113}.