LMPD Database

New search | Record Overview | Ontology/Pathway Information | Domain Information | UniProt Annotations | Related Proteins
LMP002031

UniProt Annotations

Entry Information
Gene Namealkylglycerone phosphate synthase
Protein EntryADAS_HUMAN
UniProt IDO00116
SpeciesHuman
Comments
Comment typeDescription
Catalytic Activity1-acyl-glycerone 3-phosphate + a long-chain alcohol = an alkyl-glycerone 3-phosphate + a long-chain acid anion.
CofactorName=FAD; Xref=ChEBI
DiseaseRhizomelic chondrodysplasia punctata 3 (RCDP3) [MIM
FunctionCatalyzes the exchange of an acyl for a long-chain alkyl group and the formation of the ether bond in the biosynthesis of ether phospholipids.
PathwayGlycerolipid metabolism; ether lipid biosynthesis.
SimilarityBelongs to the FAD-binding oxidoreductase/transferase type 4 family.
SimilarityContains 1 FAD-binding PCMH-type domain.
Subcellular LocationPeroxisome membrane. Note=Localized to the inner aspect of the peroxisomal membrane.
SubunitHomodimer.