LMPD Database

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LMP001966

UniProt Annotations

Entry Information
Gene Namebeta-1,4-N-acetyl-galactosaminyl transferase 2
Protein EntryB4GN2_HUMAN
UniProt IDQ8NHY0
SpeciesHuman
Comments
Comment typeDescription
Alternative ProductsEvent=Alternative splicing; Named isoforms=3; Name=1; IsoId=Q8NHY0-1; Sequence=Displayed; Name=2; IsoId=Q8NHY0-2; Sequence=VSP_017131; Name=3; IsoId=Q8NHY0-3; Sequence=VSP_045195; Note=No experimental confirmation available.;
FunctionInvolved in the synthesis of the Sd(a) antigen (Sia- alpha2,3-[GalNAc-beta1,4]Gal-beta1,4-GlcNAc), a carbohydrate determinant expressed on erythrocytes, the colonic mucosa and other tissues. Transfers a beta-1,4-linked GalNAc to the galactose residue of an alpha-2,3-sialylated chain.
PathwayProtein modification; protein glycosylation.
SimilarityBelongs to the glycosyltransferase 2 family.
Subcellular LocationGolgi apparatus membrane ; Single-pass type II membrane protein .
Tissue SpecificityWidely expressed. Highly expressed in colon and to a lesser extent in kidney, stomach, ileum and rectum.
Web ResourceName=Functional Glycomics Gateway - GTase; Note=Beta-1,4 N-acetylgalactosaminyltransferase 2; URL="http://www.functionalglycomics.org/glycomics/molecule/jsp/glycoEnzyme/viewGlycoEnzyme.jsp?gbpId=gt_hum_482";
Web ResourceName=GGDB; Note=GlycoGene database; URL="http://jcggdb.jp/rcmg/ggdb/Homolog?cat=symbol&symbol=B4GALNT2";