LMPD Database

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LMP001912

UniProt Annotations

Entry Information
Gene Namepleckstrin homology domain containing, family A (phosphoinositide binding specific) member 3
Protein EntryPKHA3_HUMAN
UniProt IDQ9HB20
SpeciesHuman
Comments
Comment typeDescription
DomainThe PH domain of FAPPS binds the small GTPase ARF1 and phosphatidylinositol-4-phosphate (PtdIns4P) with high selectivity, and is required for recruitment of FAPPs to the trans-Golgi network (TGN).
FunctionInvolved in Golgi to cell surface membrane traffic. Induces membrane tubulation. Binds preferentially to phosphatidylinositol 4-phosphate (PtdIns4P).
Sequence CautionSequence=BAA90927.1; Type=Erroneous initiation; Evidence= ;
SimilarityContains 1 PH domain. {ECO
Subcellular LocationGolgi apparatus, trans-Golgi network membrane ; Peripheral membrane protein .
SubunitInteracts with GTP-bound ARF1.
Tissue SpecificityWidely expressed.