LMPD Database

LMP001852

Gene Information

Entrez Gene ID	6720
Gene Name	sterol regulatory element binding transcription factor 1
Gene Symbol	SREBF1
Species	Homo sapiens

Gene Ontology (GO Annotations)

GO ID	Source	Type	Description
GO:0005737	ISS:UniProtKB	C	cytoplasm
GO:0031410	IEA:UniProtKB-KW	C	cytoplasmic vesicle
GO:0005829	TAS:Reactome	C	cytosol
GO:0005783	IDA:UniProtKB	C	endoplasmic reticulum
GO:0005789	TAS:Reactome	C	endoplasmic reticulum membrane
GO:0000139	TAS:Reactome	C	Golgi membrane
GO:0016021	IEA:UniProtKB-KW	C	integral component of membrane
GO:0005635	TAS:ProtInc	C	nuclear envelope
GO:0005654	TAS:Reactome	C	nucleoplasm
GO:0005634	IDA:BHF-UCL	C	nucleus
GO:0043234	IEA:Ensembl	C	protein complex
GO:0003682	IEA:Ensembl	F	chromatin binding
GO:0003677	ISS:UniProtKB	F	DNA binding
GO:0043565	IEA:Ensembl	F	sequence-specific DNA binding
GO:0003700	IDA:HGNC	F	sequence-specific DNA binding transcription factor activity
GO:0032810	IDA:HGNC	F	sterol response element binding
GO:0007568	IEA:Ensembl	P	aging
GO:0044255	TAS:Reactome	P	cellular lipid metabolic process
GO:0071398	IEA:Ensembl	P	cellular response to fatty acid
GO:0009267	ISS:HGNC	P	cellular response to starvation
GO:0008203	IEA:UniProtKB-KW	P	cholesterol metabolic process
GO:0007623	IEA:Ensembl	P	circadian rhythm
GO:0008286	IEA:Ensembl	P	insulin receptor signaling pathway
GO:0008610	ISS:UniProtKB	P	lipid biosynthetic process
GO:0006629	TAS:ProtInc	P	lipid metabolic process
GO:0030324	IEA:Ensembl	P	lung development
GO:0046676	IEA:Ensembl	P	negative regulation of insulin secretion
GO:0000122	IEA:Ensembl	P	negative regulation of transcription from RNA polymerase II promoter
GO:0045542	IEA:Ensembl	P	positive regulation of cholesterol biosynthetic process
GO:0031065	IEA:Ensembl	P	positive regulation of histone deacetylation
GO:0045944	IDA:UniProtKB	P	positive regulation of transcription from RNA polymerase II promoter
GO:0010867	ISS:UniProtKB	P	positive regulation of triglyceride biosynthetic process
GO:0019217	IEA:Ensembl	P	regulation of fatty acid metabolic process
GO:0003062	IEA:Ensembl	P	regulation of heart rate by chemical signal
GO:0006357	TAS:ProtInc	P	regulation of transcription from RNA polymerase II promoter
GO:0051591	IEA:Ensembl	P	response to cAMP
GO:0042493	IEA:Ensembl	P	response to drug
GO:0032094	IEA:Ensembl	P	response to food
GO:0033762	IEA:Ensembl	P	response to glucagon
GO:0009749	IEA:Ensembl	P	response to glucose
GO:0032570	IEA:Ensembl	P	response to progesterone
GO:0032526	IEA:Ensembl	P	response to retinoic acid
GO:0044281	TAS:Reactome	P	small molecule metabolic process
GO:0006351	IEA:UniProtKB-KW	P	transcription, DNA-templated

KEGG Pathway Links

KEGG Pathway ID	Description
hsa04152	AMPK signaling pathway
hsa04932	Non-alcoholic fatty liver disease (NAFLD)