LMPD Database

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LMP001771

UniProt Annotations

Entry Information
Gene Namephosphatidic acid phosphatase type 2C
Protein EntryLPP2_MOUSE
UniProt IDQ9DAX2
SpeciesMouse
Comments
Comment typeDescription
Alternative ProductsEvent=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q9DAX2-1; Sequence=Displayed; Name=2; IsoId=Q9DAX2-2; Sequence=VSP_009654, VSP_009655;
Catalytic ActivityA 1,2-diacylglycerol 3-phosphate + H(2)O = a 1,2-diacyl-sn-glycerol + phosphate.
FunctionCatalyzes the conversion of phosphatidic acid (PA) to diacylglycerol (DG). In addition it hydrolyzes lysophosphatidic acid (LPA), ceramide-1-phosphate (C-1-P) and sphingosine-1- phosphate (S-1-P) (By similarity). {ECO:0000250}.
SimilarityBelongs to the PA-phosphatase related phosphoesterase family. {ECO:0000305}.
Subcellular LocationMembrane; Multi-pass membrane protein.
SubunitHomodimer. {ECO:0000250}.
Tissue SpecificityExpressed at high levels in lung, liver and kidney; at low levels in heart and brain, and was not detected in skeletal muscle.