LMPD Database

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LMP001759

UniProt Annotations

Entry Information
Gene Name3-ketodihydrosphingosine reductase
Protein EntryKDSR_MOUSE
UniProt IDQ6GV12
SpeciesMouse
Comments
Comment typeDescription
Catalytic ActivitySphinganine + NADP(+) = 3-dehydrosphinganine + NADPH.
FunctionCatalyzes the reduction of 3-ketodihydrosphingosine (KDS) to dihydrosphingosine (DHS). {ECO:0000269|PubMed:15328338}.
PathwayLipid metabolism; sphingolipid metabolism.
SimilarityBelongs to the short-chain dehydrogenases/reductases (SDR) family. {ECO:0000305}.
Subcellular LocationEndoplasmic reticulum membrane; Multi-pass membrane protein.