LMPD Database

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LMP001757

UniProt Annotations

Entry Information
Gene Namealdo-keto reductase family 1, member B7
Protein EntryALD1_MOUSE
UniProt IDP21300
SpeciesMouse
Comments
Comment typeDescription
Catalytic ActivityAlditol + NAD(P)(+) = aldose + NAD(P)H.
FunctionReduces a broad range of aliphatic and aromatic aldehydes to the corresponding alcohols. May play a role in the metabolism of xenobiotic aromatic aldehydes (By similarity). The role of MVDP in sperm maturation and storage may be related to its potential capacity to produce fructose, or MVDP may play an osmoregulatory role by producing sorbitol. {ECO:0000250}.
InductionCastration resulted in a marked decrease in the level of the mRNA coding for the protein, whereas administration of testosterone to castrated males resulted in a marked increase.
SimilarityBelongs to the aldo/keto reductase family. {ECO:0000305}.
Subcellular LocationCytoplasm {ECO:0000250}.
SubunitMonomer. {ECO:0000250}.