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LMP001728

UniProt Annotations

Entry Information
Gene Namephospholipase A2-activating protein
Protein EntryPLAP_HUMAN
UniProt IDQ9Y263
SpeciesHuman
Comments
Comment typeDescription
DomainThe PFU domain mediates interaction with ubiquitin.
DomainThe PUL domain is composed of 6 armadillo-like repeats and mediates the interaction with VCP C-terminus.
FunctionInvolved in the maintenance of ubiquitin levels.
InteractionQ76353:- (xeno); NbExp=3; IntAct=EBI-1994037, EBI-6248077;
Sequence CautionSequence=AAD03030.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence= ; Sequence=AAD42075.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence= ; Sequence=AAD42075.1; Type=Frameshift; Positions=698; Evidence= ; Sequence=BAA92105.1; Type=Erroneous termination; Positions=545; Note=Translated as Gln.; Evidence= ; Sequence=BAD97264.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence= ; Sequence=CAB42881.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence= ; Sequence=CAH72641.1; Type=Erroneous gene model prediction; Evidence= ;
SimilarityBelongs to the WD repeat PLAP family.
SimilarityContains 1 PFU domain. {ECO
SimilarityContains 1 PUL domain. {ECO
SimilarityContains 6 ARM repeats.
SimilarityContains 7 WD repeats. {ECO
SubunitInteracts with ubiquitin. Interacts with VCP.