LMPD Database

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LMP001655

UniProt Annotations

Entry Information
Gene Nameprotein arginine N-methyltransferase 3
Protein EntryANM3_MOUSE
UniProt IDQ922H1
SpeciesMouse
Comments
Comment typeDescription
Alternative ProductsEvent=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q922H1-1; Sequence=Displayed; Note=No experimental confirmation available.; Name=2; IsoId=Q922H1-2; Sequence=VSP_010498;
DomainThe zinc-finger is responsible for substrate specificity. {ECO:0000250}.
Enzyme RegulationInhibited by N-ethylmaleimide and high concentrations of zinc chloride. {ECO:0000250}.
FunctionMethylates (mono and asymmetric dimethylation) the guanidino nitrogens of arginyl residues in some proteins. {ECO:0000250}.
SimilarityBelongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N- methyltransferase family. {ECO:0000255|PROSITE-ProRule:PRU01015}.
SimilarityContains 1 C2H2-type zinc finger. {ECO:0000305}.
SimilarityContains 1 SAM-dependent MTase PRMT-type domain. {ECO:0000255|PROSITE-ProRule:PRU01015}.
Subcellular LocationCytoplasm {ECO:0000250}.
SubunitMonomer or homodimer (By similarity). Interacts with EPB41L3; this inhibits methylation of target proteins. Interacts with the 40S ribosomal protein RPS2 (By similarity). {ECO:0000250}.