LMPD Database

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LMP001616

UniProt Annotations

Entry Information
Gene Namehydroxysteroid (17-beta) dehydrogenase 3
Protein EntryDHB3_MOUSE
UniProt IDP70385
SpeciesMouse
Comments
Comment typeDescription
Catalytic ActivityTestosterone + NADP(+) = androst-4-ene-3,17- dione + NADPH.
FunctionFavors the reduction of androstenedione to testosterone. Uses NADPH while the two other EDH17B enzymes use NADH (By similarity). {ECO:0000250}.
PathwayHormone biosynthesis; testosterone biosynthesis.
SimilarityBelongs to the short-chain dehydrogenases/reductases (SDR) family. 17-beta-HSD 3 subfamily. {ECO:0000305}.